时隔一年之后的2005年，Baran教授又开发了吡咯和羰基化合物的氧化

One year later, in 2005, Professor Baran developed the oxidative coupling reaction of pyrrole and carbonyl compounds. The author used ferrocene hexafluorophosphate as the oxidant and pyrrole and carbonyl compounds as the substrates to achieve a simple and fast enantioselective synthesis of the natural product (S)-Ketorolac [56]. And Professor Baran specifically mentioned in this synthesis: ketones, amides, esters and other carbonyl compounds can be used in such oxidative coupling reactions.

A year later, in 2005, Professor Baran developed a oxidation-coupled reaction of pyridoxine and carboxyl compounds. The author used hexafluorophosphate as an oxidant, with pyridoxine and niobium-based compounds as the substrates, to achieve a simple and rapid reflection of selective synthetic natural products (S)-Ketorolac purposes. And Professor Baran notes in this synthesis that several carboxyl compounds, such as ketones, alamides, and esters, can be used in these oxidation-coupled reactions.

In 2005, a year later, Professor Baran developed the oxidative coupling reaction between pyrrole and carbonyl compounds. Using ferrocene hexafluorophosphate as oxidant and pyrrole and carbonyl compounds as substrates, a simple and rapid enantioselective synthesis of natural product (s) - ketorolac was achieved. Moreover, Professor Baran specially mentioned in this synthesis that ketones, amides, esters and other carbonyl compounds can be used in such oxidative coupling reactions.<br>