Chronic administration of orexin-A aggravated cortical and hippocampal Aβ deposition in 3xTg-AD mice, which impaired object recognition memory, short-term working memory, long-term spatial learning reference memory, and fear memory.
Chronic administration of orexin-A aggravated cortical and hippocampal a in 3xTG AD mice β The object recognition memory, short-term working memory, long-term spatial learning reference memory and fear memory were impaired.
Chronic administration of orexin-A aggravated Aβ deposition in cortex and hippocampus of 3xTg-AD mice, and impaired their object recognition memory, short-term working memory, long-term spatial learning reference memory and fear memory.