o control the reaction sequence and

o control the reaction sequence and selectivity under the coexistence of reactants, intermediates, and products, the design of tandem catalysts plays a crucial role in mediating the multiple reactions under the same condition (3). In principle, a tandem catalyst is composed of different types of catalytic sites, and a predetermined sequence of reactions occurs at each corresponding catalytic site. The key to manipulating the process of tandem catalysis is to coordinate the transport of reactive intermediates among catalytic sites (4, 5). Random physical mixtures of catalysts cannot effectively mediate the reaction sequence. Therefore, the proximity (6, 7) and hierarchy (8) of catalytic sites within the tandem catalyst must be carefully constructed to regulate the transport of key intermediates