感谢reviewer有意思的提问，LPS动物模型按原计划我们准备提取基

Thank interesting questions reviewer, LPS animal model as planned we are ready to extract the hair cells on the basilar membrane test, but the actual operation, we found it impossible to extract the hair cells alone, so we cochlear cells, hair cells in the cochlea is actually contain, epithelial cells and supporting cells in mixed cell. So what kind of change does not distinguish between cells. Precisely because we later added with the LPS-stimulated HEIO-C1 cells was verified

Thanks to the interesting questions from the reviewer, the LPS animal model was prepared to extract the hair cells on the substrate membrane for testing as planned, but in practice we found that hair cells could not be extracted separately, so our cochlear cells were actually mixed cells containing cochlear hair cells, epithelial cells and supporting cells. So it's true that there's no way to tell what kind of cell changes. As a result, we later tested the HEIO-C1 cells with LPS stimulation.

Thanks to the interesting question of reviewer. According to the original plan, we are going to extract the hair cells on the basement membrane of LPS animal model for experiment, but in practice, we found that we can not extract the hair cells alone, so our cochlear cells are actually the mixed cells containing the cochlear hair cells, epithelial cells and supporting cells. So it's really impossible to tell which kind of cell changes it is. Therefore, we added LPS stimulated heio-c1 cells to verify this