At 15:03 on April 11, 2019, Yang Zhi found that the fan of standby server a was abnormal during the monthly backup of PKS system of fermentation computer in building Y108. After connecting the display to standby server a, there was no response. Forced restart of server a failed to start.<br>The most likely reason for this deviation is that the main board of server a is aging due to its long-term operation, causing server a to stop running unexpectedly.<br>Impact assessment and risk assessment in the right column: it is described as backup server, and the current value is CPU a down. According to the description, it should belong to the loss of connection between server a and main server B, and this audit trail will be generated when server a fails. "H3-tm-22528-a03 PKS fermentation computer control system audit tracking common description comparison table" does not clearly specify the status of backup server, and the data reviewers did not find the server a fault in time. In conclusion, the failure of standby server a did not affect the normal production of enramycin fermentation, and would not affect the product quality. However, "backup server" is not described in the "h3-tm-22528-a03 PKS fermentation computer control system audit tracking common description Checklist", which causes the data reviewer to fail to find the abnormality in time, so it is necessary to supplement this SOP.<br>Since the primary server B is the first choice for the operation of fermentation computer in building Y108, the standby server a only intervenes when the primary server B fails or is unable to operate due to other reasons. Therefore, during the failure of standby server a, the parameters, historical data and audit trail of all operation tanks operate normally on the primary server B, which has no impact on the production of enramycin. Since the maintenance of standby server a only involves replacing the main board, when the maintenance of server a is completed, the fermentation system will automatically synchronize to the main server B, all parameters and settings have not changed, and the fermentation system will return to the normal redundant design, which will not affect the subsequent production. Fermentation personnel have verified the historical data and audit trail between March 29, 2019 and April 5, 2019, and the record shows that no abnormality is found. Check the audit trail and historical curve between March 31, 2019 and April 15, 2019 again, no abnormal events and data loss are found. After the re investigation of audit trail, it was found that there was a systematic audit trail at 14:05 on March 31, 2019, described as server_115, source as rendant, and the root cause of the deviation in the left column later.<br>1. Replace the main board of server a.<br>2. Revise "h3-tm-22528-a03 PKS fermentation computer control system audit tracking common description Checklist" and add the description information of backup server.
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