The median time to first onset of any Grade diarrhea was 2 days (range, 1-320) and the median time to first onset of Grade ≥ 3 diarrhea was 8 days (range, 1-350). The median cumulative duration of any Grade diarrhea was 59 days (range, 1-523) and the median cumulative duration of Grade ≥ 3 diarrhea was 5 days (range, 1-139).