For sterile preparations, leakage means the entry of outside air, which will bring fungi, bacteria, etc. As a result, microbial contamination occurs, or endotoxin exceeds the standard. Once used, endotoxin can cause fever in patients, ranging from systemic blood infection to severe systemic blood infection. This point of view has been confirmed in the analysis of the causes of clinical infusion reactions. The hidden danger of large-volume injection leakage is the leakage of liquid medicine caused by poor sealing. The leakage of injections is not only a simple large amount of liquid leakage, but also includes tiny leakage that is not easy to detect with the naked eye. Leakage will result in microbial contamination of the product, endangering patient safety.
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