It is a goal pursued by chemists and materials scientists to build a material system with specific functions through precise chemical design and directed synthesis. Understanding of the chemical bonding, spatial structure and interactions at the atomic and molecular levels in coordination chemistry not only helps to understand the structure-activity relationship of materials, but also directional design and improvement of the function of materials, that causes the coordination-directed molecular-based material to become the link between the chemistry and the material. As a diversified and designable zero-dimensional organic-inorganic hybrid system, the coordination molecule cluster can get a unique bionic hub like the cube, by designing and regulating organic ligands and metal ions. Achieve its specific functional loading and modification in the fields of luminescence, magnetism and catalysis. However, due to the unique structure of the cube, the stability and excellent performance of the structure cannot be obtained at the same time. Designing and synthesizing CUBE with good stability and excellent activity is a challenge