[摘要]糖尿病视网膜病变(DiabeticRefinopathy, D

[Abstract] Diabetic <br><br>Refinopathy (DR) is the most common complication of diabetes. Over the years, the research on its pathogenesis has mainly focused on the changes of retinal capillary microcirculation, and there are few studies on retinal nerve tissue. In the mid-1980s, scholars have proposed that the main pathogenesis of DR may not only be the retinal blood vessels themselves, but also have a closer relationship with neurons or glial tissues around the blood vessels. The neurons and/or glial of the retina may be particularly sensitive to the effects of long-term hyperglycemia, micro <br><br>[keywords] retinal ganglion cells; diabetes; retinopathy; apoptosis; neurotrophic factors

Diabetic retinal lesions (Diabetic<br><br>Refinopathy, DR) is the most common complication of diabetes. Over the years, the study of its pathogenesis has mainly focused on the change of the microcirculation of retinal capillaries, and few studies have been made on retinal nerve tissue. In the mid-1980s, scholars suggested that the main pathogenesis of DR might be not only the retinal blood vessels themselves, but also around the blood vessels. neurons or glial tissues are more closely related. Neurons and/or glials in the retina may be particularly sensitive to long-term hyperglycemia effects<br><br>Retinal nerve cells; diabetes; retinal lesions; apoptosis; neurotrophic factors

[Abstract] Diabetic Retinopathy<br>DR is the most common complication of diabetes. For many years, the research on its pathogenesis mainly focuses on the changes of retinal capillary microcirculation, but less on retinal nerve tissue. In the mid-1980s, some scholars have proposed that the main pathogenesis of DR is not only retinal vessels themselves, but also closely related to neurons or glial tissue around the vessels. Retinal neurons and / or glia may be particularly sensitive to long-term hyperglycemia<br>[Key words] retinal ganglion cells; diabetes mellitus; retinopathy; apoptosis; neurotrophic factor<br>