Fig. 2. FT-Raman spectra of the fou

图2.四种分析的商业双氯芬酸钠注射液的FT-拉曼光谱D为构建如上所述制备的28个样品的校准模型光谱。选择了六种混合物进行验证，其他六种被视为“未知”样品。双氯芬酸钠的浓度范围为1-4％，丙二醇的浓度范围为10-28％，苯甲醇的浓度范围为1-5％，NaOH，d-甘露糖醇和焦亚硫酸钠的水溶液浓度范围为64-83％。<br><br>第二个分析系统仅包含三种物质。氨茶碱是茶碱与乙二胺（2：1）的复合物，溶于水。如前所述，它可能含有过量的乙二胺。在稀氨茶碱溶液的光谱中，在564和683 cm-1处只有两个峰，对于活性化合物清晰可见（图3）。为了清晰起见，光谱偏移了0.5。

Fig. 2. FT-Raman spectra of the four analysed commercial diclofenac sodium injection solutions DTo construct the calibration models spectra of 28 samples, prepared as described above were used. Six mixtures were chosen for the validation procedure and six other were treated as “unknown” samples. The concentration varied in the range 1–4% for diclofenac sodium, 10–28% for propylenediol, 1–5% for benzyl alcohol and 64–83% for the aqueous solution of NaOH, d-mannitol and sodium pyrosulfite.<br><br>The second analysed system consists of three substances only. Aminophylline, which is a complex of theophylline with ethylenediamine (2:1) is dissolved in water. As mentioned before, it may contain an excess of ethylenediamine. In the spectra of diluted aminophylline solutions there are only two peaks at 564 and 683 cm−1, clearly visible for the active compound (Fig. 3).1–D4; the spectra are offset for clarity by 0.5.

图2。用上述方法制备的4种市售双氯芬酸钠注射液的FT-Raman光谱对28个样品的光谱进行了dt构模。选择6种混合物作为验证程序，另外6种作为“未知”样品。双氯芬酸钠的浓度范围为1-4%，丙二醇的浓度范围为10-28%，苯甲醇的浓度范围为1-5%，氢氧化钠、d-甘露醇和焦亚硫酸钠水溶液的浓度范围为64-83%。<br>第二个分析系统仅由三种物质组成。氨茶碱是茶碱与乙二胺（2:1）的络合物，溶于水。如前所述，它可能含有过量的乙二胺。在稀释氨茶碱溶液的光谱中，在564和683 cm-1处只有两个峰，活性化合物清晰可见（图3.1-D4）；光谱偏移0.5以保持清晰。<br>