New use of old medicine-nifedipine by acting on TRPs family and inflammatory proteins in the treatment of chilblainhas been seen by the editors. They decided that the manuscript be not accepted on the basis of low priority.Due to the number of manuscripts submitted to the EUROPEAN JOURNAL OF PHARMACOLOGY, the journal restricts its scope, with the emphasis on mechanisms of action as the main topic.Strict priorities are assigned to the manuscripts submitted.We therefore regret that we cannot accept your manuscript for publication.Decisions based on priorities are final, and thus not open to appeal.Nonetheless, I thank you for having submitted your manuscript to the European Journal of Pharmacology.