Spunlacing is a promising nonwoven technology for the production of fabric with good handle and better structural integrity. Structural parameters such as pore size, thickness and number of binding point/entanglement between fibres are decisive for good mechanical and comfort properties of nonwoven fabrics. This study aims to focus on the effect of different process parameters on the structural change in spunlace fabrics.; ; Spunlacing is purely a mechanical bonding technology where high-speed jets of water strike a web to entangle the fibres. Different spunlace nonwoven structures were produced by varying processing parameters such as waterjet pressure, delivery speed, web mass and web composition as per four-factor, three-level Box–Behnken design. The effect of these parameters on the structural arrangement was studied using scanning electron microscopy. An attempt has also been made to study the changes in pore geometry and thickness of the fabrics by using response surface methodology with backward elimination.; ; Significant structural changes were observed with variation in water pressure, web mass and web composition. The test results showed that fabric produced at higher waterjet pressure has lower mean pore diameter and lower thickness. The variation in mean pore diameter and mean thickness due to waterjet pressure is around 26 and 34 per cent, respectively, at 95 per cent significance level.