Lowering blood pressure has been shown to decrease retinopathy progression, although tight targets (systolic blood pressure ,120 mmHg) do not impart additional benefit (106). ACE inhibitors and ARBs are both effective treatments in diabetic retinopathy (126). In patients with dyslipidemia, retinopathy progression may be slowed by the addition of fenofibrate, particularly with very mild nonproliferative diabetic retinopathy at baseline (104,127).