Abstract:ThemechanismofPreferentialEnrichment,anunusualenantiomericresolutionphenomenonobserveduponrecrystallizationofaseriesofracemiccrystalswhichareclassifiedasaracemicmixedcrystalwithfairlyorderedarrangementofthetwoenantiomers,hasbeenstudied.Onthebasisoftheexistenceofpolymorphsandtheoccurrenceoftheresultingpolymorphictransitionduringcrystallizationfromsolution,themechanismhasbeenaccountedforintermsof(1)apreferentialhomochiralmolecularassociationtoformone-dimensionalchainstructuresinthesupersaturatedsolutionoftheracemateornonracemicsamplewithaloweevalue