Membrane permeabilizationColistin,

膜通透性<br>Colistin，一种已知的膜置换剂，被用作阳性对照，并迅速导致铜绿假单胞菌的细胞质膜去极化，如高荧光水平所确定（图2）。在MIC（11.8 mM）处，CAD的结果与粘菌素相似（图2）。5.9 mM的CAD结果与未处理的对照相似。因此，可以得出结论，CAD在MIC处使铜绿假单胞菌的细胞质膜去极化，而在亚MIC处（5.9 mM）则没有。

Membrane permeabilization<br>Colistin, a known membrane displacement agent, was used as a positive control and rapidly led to depolarization of the cytoplasmic membrane of P. aeruginosa, as determined by high fluorescence levels (Fig. 2). At the MIC (11.8 mM), CAD gave similar results to colistin (Fig. 2). The result for CAD at 5.9 mM was similar to that for the untreated control. Thus, it was concluded that CAD depolarized the cytoplasmic membrane of P. aeruginosa at the MIC, but not at a sub-MIC (5.9 mM).

膜渗透性<br>大肠杆菌素，一种已知的膜置换剂，被用作阳性对照，通过高荧光水平测定，迅速导致铜绿假单胞菌胞质膜去极化（图2）。在MIC（11.8 mM）时，CAD给出的结果与colistin相似（图2）。5.9 mM处的CAD结果与未经治疗的对照组相似。因此，CAD在MIC处使铜绿假单胞菌胞质膜去极化，而在亚MIC（5.9 mM）处不去极化。<br>