[摘要] 目的：探讨养血清脑颗粒对脑梗死后抑郁症患者神经功能及血清指标

[Abstract] Objective: To investigate the effects on the nervous YANGXUEQINGNAOKELI patients with depression and serum after cerebral infarction. Methods: June 2016 - June 2019 after cerebral infarction depression included 100 patients in our hospital as research subjects, divided into two groups according to random number table, the control group on the basis of conventional therapy plus Paluoxiting treatment; observation group YANGXUEQINGNAOKELI treatment group based on the use, respectively, using Princeton Hamilton depression scale (HAMD) after treatment, Hamilton anxiety scale (HAMA), neurological deficit scores stroke scale (NIHSS ) scored two groups of patients before and after treatment were compared in patients with cortisol, noradrenaline (NE), Dopamine (DA) and 5-hydroxytryptamine (5-HT) levels. Results: After treatment, both groups NIHSS, HAMD, HAMA score, significantly lower cortisol levels than those before treatment, observation group was significantly lower than control group (P <0.05), two groups of 5-HT, DA and NE were significantly increased, and the observation group was significantly higher (P <0.05); groups rate of adverse reactions was no significant difference (P> 0.05). Conclusion: YANGXUEQINGNAOKELI joint Paluoxiting can improve neurological function in patients with depression after cerebral infarction, regulate a number of indicators in serum levels of 5-HT, etc., to improve the symptoms of anxiety and depression in patients with significant effect without increasing side effects.

Objective: To explore the effects of serum brain particles on neurofunction and serum indicators in patients with depression after cerebral infarction. Methods: Selected 100 patients with post-mortem depression in our hospital from June 2016 to June 2019 as the subject situ, divided into two groups according to the random numerical table, and the control group was treated with paroxetine on the basis of conventional treatment; Two groups of patients were graded with Hameston Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and Stroke Neurodesive Score Scale (NIHSS) before and after treatment, comparing both groups of patients with cortisol, Norlineadrena (NE), Dopamine (DA) and 5-hydroxytryptamine (5-HT) levels. Results: After treatment, the average level of NIHSS, HAMD, HAMA score and cortisol water was significantly lower than before treatment, and the observation group was significantly lower than that of the control group (both P 0.05), and both groups of 5-HT, DA and NE were significantly increased. The observation group was significantly higher than the control group (both P 0.05) and there was no significant difference in the adverse reaction rate of the two groups (P.05). Conclusion: The combination of serum brain particles and paroxetine can effectively improve the neurofunction of patients with depression after cerebral infarction, regulate the level of 5-HT and other indicators in serum, and improve the effect of anxiety depressive symptoms in patients without increasing adverse reactions.

[Abstract] Objective: To explore the effect of Yangxueqingnao Granule on the neurological function and serum indexes of patients with depression after cerebral infarction. Methods: 100 patients with post cerebral infarction depression included in our hospital from June 2016 to June 2019 were selected as the research objects, and divided into two groups according to the random number table method. The control group was treated with paroxetine on the basis of conventional treatment; the observation group was treated with Yangxueqingnao Granule on the basis of the control group, and the Hamilton Depression Scale (HAMD), Hamilton Joule were used before and after treatment respectively The levels of cortisol, noradrenaline (NE), dopamine (DA) and 5-hydroxytryptamine (5-HT) were compared before and after treatment. Results: after treatment, NIHSS, HAMD, HAMA scores and cortisol levels of the two groups were significantly lower than those before treatment, and the observation group was significantly lower than the control group (P < 0.05), 5-HT, DA and ne of the two groups were significantly increased, and the observation group was significantly higher than the control group (P < 0.05); there was no significant difference between the two groups (P > 0.05). Conclusion: Yangxueqingnao Granule Combined with paroxetine can effectively improve the neurologic function of patients with depression after cerebral infarction, regulate the level of 5-HT and other indicators in serum, improve the symptoms of anxiety and depression of patients significantly, and do not increase adverse reactions.<br>