To our knowledge, no studies have b

To our knowledge, no studies have been adequately powered to assess whether intrahepatic cholestasis of pregnancy -associated fetal death occurs above a certain bile acid threshold, and clinical guidelines are largely reliant upon expert consensus to determine the optimal management of affected women.12,13 Clinicians often recommend management ranging from surveillance to iatrogenic delivery to prevent the subsequent risk of fetal death, at gestations typically between 36 weeks and 40 completed weeks, although the evidence behind this approach is scarce.14 Certainly, early delivery is associated with short-term neonatal problems and long-term issues with impairments in educational performanceshown with even early-term birth.1