which reduce metal ions to nanoparticles and stabilize them. Plant extracts are easily available and can beeasily scaled up for industrial synthesis with less contamination. There have been several reports for the growth of metalnanoparticles by biosynthesis using different plant extracts[16–24]. The major challenge in design biosynthesis of thenanoparticle is to have proper control over size and morphology of the nanoparticles by controlling the reactionconditions.Therefore, we used Cinnamon zeylanicum bark for the biosynthesis of AgNPs. The bark is widely used as a spice incooking and also as medicinal used to treat diarrhea and otherproblems of the digestive system. The bark extracts contain ahigh concentration of cinnamaldehyde, eugenol, and linaloolwith high-antioxidant activity [25]. The aim of this presentinvestigation is to explore the responsible factor inCinnamon zeylanicum bark extract for morphological controlof AgNPs and to investigate the various chemicals involved inthe bioreduction [26, 27]. Cinnamon zeylanicum barks wereextracted in different solvents having different polarities, i.e.,aqueous, ethanol, and DMSO, and then the reduction of silverions was estimated. Recently, influence of different solventsover the synthesis of cinnamon nanoparticles was investigatedand observed that the variation of solvent medium altered themorphology of the nanoparticles [28]. The relationship amongantioxidant activity, total phenolic content, and aldehyde content for each solvent extract were investigated. The synthesized AgNPs were characterized by using spectral analysislike UV–vis spectroscopy, HRTEM, and energy-dispersiveX-ray analysis (EDX). Furthermore, the biosynthesizedAgNPs were tested for their antibacterial activity againstE. coli and S. aureus strains. The major finding of this workis related to the identification of specific biochemicals presentin the extracts involved in the reduction and stabilization ofAgNPs and their antimicrobial activity