In our study, Western-blot results were consistent with RT-qPCR results, which showed that Breviscapine inhibited the expression of PXR and CYP3A4 mRNA in the same trend. When Changbranches (10, 20, 40, 80 μM) were used to treat Chang hepatocytes After 24 hours, the expression of CYP2C19 and CAR mRNA was promoted.
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