As mentioned, the discovery of the male‐inducing role of the mammalian and human Y chromosome in 1959, deduced from the phenotypes of Ullrich–Turner and Klinefelter syndromes, appeared to confirm the concept of the male as the induced state. At the time less attention was paid to the fact that in Ullrich–Turner syndrome the phenotype is not that of a normal female, nor in Klinefelter syndrome that of a normal male.