IntroductionIntroducing siRNA duplexes into cells efficiently requires the involvement of a transfection reagent. OriGene has developed a proprietary catonic lipid based transfection reagent, siTran 1.0, for this purpose. siTran 1.0 transfects siRNA into mammalian cells with a high efficiency and has no reported negative effects on cell viability (Fig. 1 A, 1B). siTran 1.0 also displays high efficiency for transfecting plasmid DNA into cells (Fig. 2A). This dual functionality allows one to easily conduct experiments requiring co-transfection of siRNA and plasmid DNA.