In the development of lung cancer,

In the development of lung cancer, due to the lack of effective early screening and diagnosis of tumor molecular markers, most of the patients with clinical diagnosis of lung cancer are late, leading to patients missing the best opportunity for treatment, so that the survival rate is significantly reduced. A large number of studies have shown that there are some miRNAs in the blood of patients with lung cancer, which are expected to screen biomarkers of early lung cancer through high-throughput sequencing and apply to the early diagnosis and treatment of lung cancer. Analysis of miRNA at different expression levels is helpful to understand the pathogenesis of lung cancer and elucidate the role of miRNA in lung cancerAccording to the high-throughput sequencing data of our research group, mir-20b was selected as the research object by comparing the expression level of miRNA in the whole genome between lung cancer tissue and normal lung tissue samples, and verified in TCGA database. In this chapter, we studied the expression of mir-20b in NSCLC patients' plasma and lung cancer cell lines.

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结果 (简体中文) 1: [复制]

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在肺癌的发展中，由于缺乏有效的早期筛查和肿瘤分子标志物的诊断方法，大多数临床诊断为肺癌的患者都处于晚期，导致患者错过了最佳的治疗机会，从而使生存率下降大大减少了。大量研究表明，肺癌患者血液中存在一些miRNA，有望通过高通量测序来筛选早期肺癌的生物标志物，并将其应用于肺癌的早期诊断和治疗。分析不同表达水平的miRNA有助于了解肺癌的发病机理，阐明miRNA在肺癌中的作用 根据研究小组的高通量测序数据，通过比较肺癌组织和正常肺组织样本中全基因组中miRNA的表达水平，选择mir-20b作为研究对象，并在TCGA数据库中进行了验证。在本章中，我们研究了mir-20b在非小细胞肺癌患者血浆和肺癌细胞系中的表达。

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结果 (简体中文) 2:[复制]

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In the development of lung cancer, due to the lack of effective early screening and diagnosis of tumor molecular markers, most of the patients with clinical diagnosis of lung cancer are late, leading to patients missing the best opportunity for treatment, so that the survival rate is significantly reduced. A large number of studies have shown that there are some miRNAs in the blood of patients with lung cancer, which are expected to screen biomarkers of early lung cancer through high-throughput sequencing and apply to the early diagnosis and treatment of lung cancer. Analysis of miRNA at different expression levels is helpful to understand the pathogenesis of lung cancer and elucidate the role of miRNA in lung cancer According to the high-throughput sequencing data of our research group, mir-20b was selected as the research object by comparing the expression level of miRNA in the whole genome between lung cancer tissue and normal lung tissue samples, and verified in TCGA database. In this chapter, we studied the expression of mir-20b in NSCLC patients' plasma and lung cancer cell lines.

正在翻译中..

结果 (简体中文) 3:[复制]

复制成功！

在肺癌的发展过程中，由于缺乏有效的肿瘤分子标志物早期筛查和诊断，多数肺癌患者临床诊断较迟，导致患者错过了最佳治疗时机，使生存率明显降低。大量研究表明，肺癌患者血液中存在一些mirna，有望通过高通量测序筛选早期肺癌的生物标志物，应用于肺癌的早期诊断和治疗。分析不同表达水平的miRNA有助于了解肺癌的发病机制，阐明miRNA在肺癌中的作用 根据本研究组高通量测序数据，通过比较肺癌组织和正常肺组织标本全基因组miRNA的表达水平，选择mir-20b作为研究对象，并在TCGA数据库中进行验证。在本章中，我们研究了mir-20b在NSCLC患者血浆和肺癌细胞系中的表达。

正在翻译中..

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