A 52-year-old man, former smoker, presented with a 2-month history of asymmetric polyarthralgia, myalgia, andweight loss of 8 kg associated with progressive dyspnea,orthopnea, and dysphonia. Additionally, the patient had anincreasing weakness of the muscles of the pelvic and shoul-der girdles given by the inability to perform activities suchas climbing stairs, standing up, driving, opening doors,shaving, washing his face, and tying his shoes.