In addition to the promotion of periodontal bone regeneration by the anti-inflammatory microenvironment, ASTA may have played a direct role. Studies have shown that ASTA may inhibit the formation of osteoclasts by expressing nuclear factor of activated T cells (NFAT-c1), dendritic cell-specific transmembrane protein (DC-STAMP), TRAP and cathepsin K, and can also increase bone Expression of fibronectin, osteopontin, promotes calcium deposition and osteogenesis54,55.
正在翻译中..