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BackgroundHip arthroplasty (HA), in
Background
Hip arthroplasty (HA), including total hip arthroplasty and semi-hip arthroplasty, is one of the most common surgical procedures performed in geriatric femoral neck fracture. Although HA is a safe, effective procedure, a small percentage of HA procedures do result in major complications, including pneumonia, surgical site infection(SSI), wound dehiscence, prosthetic joint infection(PJI), heart failure, and death [1–4]. Prior studies have identified respiratory disease, older age, diabetes mellitus, and prior infection as risk factors for postoperative complications [1, 5–8].
Malnutrition has been identified as another potential risk factor for poor outcomes. It has been shown to increase the risk of SSI, wound dehiscence, and PJI [4, 9, 10]. Unfortunately,
it has been shown that more than half of in-hospital geriatric patients present with malnutrition [11]. Hypoalbuminemia (serum albumin concentration < 3.5 g/dL) is most commonly used serum marker of malnutrition [12]. It has shown that the percentage of hypoalbuminemia in elderly patients with hip fracture is nearly 50% [13, 14].
Although hypoalbuminemia is potentially modifiable before the operation, it is difficult to achieve for a limited time for the purpose of reducing complications (such as pneumonia, deep vine thrombosis) due to prolonged bed rest in geriatric femoral neck fracture patients.
Current nutrition guidelines state that oral nutritional supplements are recommended in geriatric patients after hip fracture and orthopedic surgery to reduce complications [14–16]. However, contradictory results have found. Several studies, including RCT (randomized placebo-controlled test) [17], indicated beneficial effects of nutritional status, hospital stay, clinical outcome, and mortality [17–20]. Other studies failed to demonstrate these [19, 21]. A recent meta-analysis included 41 trials and 3881 participants, the results showed low-quality evidence of nutritional supplementation on complications and mortality [22].
The heterogeneity of included patients and surgical procedures may be a significant limitation to delineate accurate conclusion [22]. The purpose of this study was to retrospectively investigate the effect of oral supplementation of enteral nutritional powder on the complications of geriatric femoral neck fracture with hypoalbuminemia.We analyzed the effect of nutritional supplementation on a particular cohort to decrease heterogeneity
Hip arthroplasty (HA), including total hip arthroplasty and semi-hip arthroplasty, is one of the most common surgical procedures performed in geriatric femoral neck fracture. Although HA is a safe, effective procedure, a small percentage of HA procedures do result in major complications, including pneumonia, surgical site infection(SSI), wound dehiscence, prosthetic joint infection(PJI), heart failure, and death [1–4]. Prior studies have identified respiratory disease, older age, diabetes mellitus, and prior infection as risk factors for postoperative complications [1, 5–8].
Malnutrition has been identified as another potential risk factor for poor outcomes. It has been shown to increase the risk of SSI, wound dehiscence, and PJI [4, 9, 10]. Unfortunately,
it has been shown that more than half of in-hospital geriatric patients present with malnutrition [11]. Hypoalbuminemia (serum albumin concentration < 3.5 g/dL) is most commonly used serum marker of malnutrition [12]. It has shown that the percentage of hypoalbuminemia in elderly patients with hip fracture is nearly 50% [13, 14].
Although hypoalbuminemia is potentially modifiable before the operation, it is difficult to achieve for a limited time for the purpose of reducing complications (such as pneumonia, deep vine thrombosis) due to prolonged bed rest in geriatric femoral neck fracture patients.
Current nutrition guidelines state that oral nutritional supplements are recommended in geriatric patients after hip fracture and orthopedic surgery to reduce complications [14–16]. However, contradictory results have found. Several studies, including RCT (randomized placebo-controlled test) [17], indicated beneficial effects of nutritional status, hospital stay, clinical outcome, and mortality [17–20]. Other studies failed to demonstrate these [19, 21]. A recent meta-analysis included 41 trials and 3881 participants, the results showed low-quality evidence of nutritional supplementation on complications and mortality [22].
The heterogeneity of included patients and surgical procedures may be a significant limitation to delineate accurate conclusion [22]. The purpose of this study was to retrospectively investigate the effect of oral supplementation of enteral nutritional powder on the complications of geriatric femoral neck fracture with hypoalbuminemia.We analyzed the effect of nutritional supplementation on a particular cohort to decrease heterogeneity
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背景<br>髋关节成形术（HA），其中包括全髋关节置换和半髋关节置换术，是在老年股骨颈骨折执行的最常见的外科手术之一。尽管HA是一种安全，有效的方法，房委会的小程序的百分比也导致严重的并发症，包括肺炎，手术部位感染（SSI），伤口裂开，人工关节感染（PJI），心脏衰竭，甚至死亡[1-4 ]。此前的研究已经确定了呼吸系统疾病，年龄大，糖尿病，和先前感染为术后并发症[1，5-8]危险因素。<br>营养不良已经被确定为不良后果的另一个潜在的危险因素。它已被证明能增加SSI的风险，伤口裂开，并PJI [4,9，10]。不幸，<br>已经显示，超过一半的院内本营养不良[11]老年患者。低蛋白血症（血清白蛋白浓度<3.5克/分升）是最常用的营养不良[12]的血清标记。它表明，在老年患者髋部骨折低白蛋白血症的百分比接近50％[13，14]。<br>虽然低白蛋白血症是在操作前潜在修改的，这是难以实现在有限的时间用于减少并发症（如肺炎，深藤血栓形成）由于老年股骨颈骨折病人长期卧床休息的目的。<br>当前营养指南指出，口服营养补充剂在老年患者推荐的髋部骨折和骨科手术后，减少并发症[14-16]。然而，矛盾的结果发现。一些研究，包括RCT（随机安慰剂对照试验）[17]，表明营养状况，住院天数，临床疗效和死亡率[17-20]有益的作用。其他的研究未能证明这些[19，21]。最近的一项荟萃分析包括41个试验和3881人参加，结果显示对并发症和死亡率[22]营养补充的低质量的证据。<br>包括患者和外科手术的异质性可以描绘准确的结论[22]一个显著限制。本研究的目的是调查回顾性肠营养粉的口服补充剂对老年股骨颈骨折的hypoalbuminemia.We分析上的特定队列营养补充品的效果降低的异质性并发症的影响
正在翻译中..
背景<br>髋关节整形术（HA），包括全髋关节整形术和半髋关节关节整形术，是老年股骨颈部骨折中最常见的外科手术之一。虽然医管局是一个安全、有效的程序，但一小部分医管局程序确实会导致重大并发症，包括肺炎、手术部位感染（SSI）、伤口失血、假肢关节感染（PJI）、心力衰竭和死亡[1⁄4]。先前的研究已经确定呼吸系统疾病、老年、糖尿病和先前感染是术后并发症的危险因素[1，5[8]。<br>营养不良已被确定为不良结果的另一个潜在风险因素。它已被证明会增加 SSI、伤口脱伤和 PJI [4， 9， 10] 的风险。不幸<br>研究表明，超过半数的住院老年病患者存在营养不良[11]。低白蛋白血症（血清白蛋白浓度 = 3.5 g/dL）是营养不良最常用的血清标记[12]。结果表明，髋部骨折老年患者的低蛋白血症比例接近50%[13，14]。<br>虽然在手术前，低白蛋白血症是有可能改变的，但很难在有限的时间内减少并发症（如肺炎、深藤血栓形成），因为老年股骨颈部骨折的卧床休息时间较长患者。<br>目前的营养指南规定，在髋关节骨折和骨科手术后，建议老年患者使用口服营养补充剂，以减少并发症[14[16]。然而，矛盾的结果已经发现。几项研究，包括RCT（随机安慰剂对照测试）[17]，表明营养状况、住院、临床结果和死亡率的有益影响[17[20]。其他研究未能证明这些[19，21]。最近的荟萃分析包括41项试验和3881名参与者，结果显示，在并发症和死亡率方面补充营养的低水平证据[22]。<br>包括的患者和外科手术的异质性可能是界定准确结论的一个重大限制[22]。本研究旨在回顾性地研究口服补充肠道营养粉对低血症老年股骨颈部骨折并发症的影响。我们分析了营养补充对特定队列的影响，以减少异质性
正在翻译中..
背景<br>髋关节置换术（ha）包括全髋关节置换和半髋关节置换，是老年股骨颈骨折最常见的手术方式之一。尽管透明质酸是一种安全、有效的治疗方法，但有一小部分透明质酸治疗会导致严重并发症，包括肺炎、手术部位感染（ssi）、伤口裂开、人工关节感染（pji）、心力衰竭和死亡[1-4]。先前的研究已经确定呼吸道疾病、老年人、糖尿病和既往感染是术后并发症的危险因素[1，5–8]。<br>营养不良被认为是导致不良结果的另一个潜在危险因素。它已经被证明增加了ssi，伤口裂开，和pji的风险[4，9，10]。不幸的是，<br>有研究表明，超过一半的住院老年患者存在营养不良[11]。低蛋白血症（血清白蛋白浓度<3.5g/dl）是营养不良最常用的血清标志物[12]。研究表明，老年髋部骨折患者低蛋白血症的比例接近50%[13，14]。<br>虽然低蛋白血症在术前是可以改变的，但由于老年股骨颈骨折患者长时间卧床休息，很难在有限的时间内达到降低并发症（如肺炎、深静脉血栓形成）的目的。<br>目前的营养指南规定，建议老年髋部骨折和骨科手术后患者口服营养补充剂，以减少并发症[14–16]。然而，却发现了相互矛盾的结果。一些研究，包括随机安慰剂对照试验（RCT）[17]，表明营养状况、住院时间、临床结果和死亡率的有益影响[17-20]。其他研究未能证明这些[19，21]。最近的荟萃分析包括41个试验和3881名参与者，结果显示营养补充对并发症和死亡率的低质量证据[22]。<br>纳入患者和手术程序的异质性可能是描述准确结论的一个重要限制[22]。本研究的目的是回顾性地探讨口服肠内营养粉对老年股骨颈骨折合并低蛋白血症并发症的影响。我们分析了营养补充对特定人群的影响，以减少异质性。<br>
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