This blood oxygen infusion injection method is much simpler (no moving or powered parts) and cheaper than the manufacture and operation of the lung ventilator, making it easily available and applicable in many different healthcare environments around the world. The correct and optimised IV delivery rate could be determined from pulse oximeter readings for blood oxygen saturation. Thus, we propose an innovation utilising the intravenous injection route coupled with nanobubble technology, which could maintain blood oxygen pressure at normal levels safely and easily without the need for ventilators. Theoretical Data analysis indicated that intravenous delivery of 400 ml oxygen nanobubble physiological saline solution (ONPS) containing 40 mg O2/L can improve low oxygen blood pressure (PaO2) from 0.133 kPa (typical for critical patients) to a normal level of 13.3 kPa (normal people). Notably, the intravenous infusion contains only pure oxygen and physiological saline solution without adding any other chemical or biological reagents or drugs.