In this paper, oat was used as the main raw material, and sensory score was used as the evaluation standard. Through single factor test, the effects of different wine dosage, fermentation time and fermentation temperature on the flavor quality of oat rice wine were analyzed. On this basis, the orthogonal test was designed to analyze the best process, and the alcohol content, total acid, reducing sugar, total bacterial count and coliform group were determined. The results showed that the solid rice wine with complete body, bright yellow color, harmonious and pure flavor and unique style could be obtained after fermentation when the amount of wine added in oat was%, fermentation time was h and fermentation temperature was ℃. So as to broaden the application of oats, and provide a theoretical basis for the development of oats rice wine.