• Screening for depression can be done using the HADS (Hospital Anxiety & Depression Scale) or may be as simple as using the single item depression screen: o Single-item – “Have you been depressed most of the time for the past two weeks?” or “Are you depressed?” (an answer ‘yes’ is a positive screen)• Risk factors for depression include: o Inadequate symptom controlo Poor quality of lifeo Lack of social support o Past and/or family history of depression o Older age o Misinformed prognosis o Drugs (steroids, cytotoxics, neuroleptics, sedatives) o Immobility o Advanced malignant disease