菌株方面拟从四个路线进行（1） 以黄曲霉毒素B1的结构类似物香豆素为唯

In terms of strains, it is planned to proceed from four routes <br>(1) Using coumarin, a structural analogue of aflatoxin B1, as the sole carbon source and energy source, it is necessary to treat the places where aflatoxin is easy to infest such as peanut soil, animal feces, Preliminary screening and enrichment of moldy corn and other strains, or use of moldy peanuts and other substrates to capture and enrich in the environment, re-screening with peanut meal, the actual target, to obtain strains that can truly degrade aflatoxin B1; <br>(2) Collect commercially available strains Commodities, conduct detoxification evaluation with peanut meal as the object of action; <br>(3) Evaluation with potential partners; <br>(4) Collection of corresponding strains in literature and patent reports for detoxification evaluation; <br>on the basis of screening detoxified strains In terms of fermentation process, fermentation processes such as water activity, nutritional factors, and detoxification enzyme activation methods are further optimized to achieve the improvement of detoxification efficiency.

The strain is intended to be carried out from four routes<br>(1) To aflatoxin B1 structure similar to coumulon as the only carbon source and energy, according to the principle of all things living in the same grams, aflatoxin easy to infest places such as peanut soil, animal droppings, moldy corn, etc. for the initial screening of strains rich, or to moldy peanuts and other substrates in the environment to capture rich, to the actual effect of peanut meal re-screening, to obtain a real degradation of aflatoxin B1 strains;<br>(2) Collecting commercially available commodities, taking peanut meal as the object of action, and conducting detoxification evaluation;<br>(3) Assessment with potential partners;<br>(4) Collecting the corresponding strains reported in literature and patents for detoxification evaluation;<br>On the basis of screening out detoxifying strains, fermentation processes such as moisture activity, nutritional factors and detoxase activation methods are further optimized to achieve the improvement of detoxification efficiency.

菌株方面拟从四个路线进行（1） 以黄曲霉毒素B1的结构类似物香豆素为唯一碳源和能源，依据万物相生相克的原理对黄曲霉菌容易出没的地方如花生土壤、动物粪便、发霉玉米等进行菌株初步筛选富集，或者以发霉花生等基质在环境中捕获富集，以实际作用对象花生粕进行复筛，获得真正能够降解黄曲霉毒素B1的菌株；（2） 收集市售商品，进行以花生粕为作用对象，进行脱毒评价；（3） 与潜在合作对象进行评估；（4） 搜集文献和专利报道的相应菌株，进行脱毒评价；在筛选出脱毒菌株基础上，发酵工艺方面拟水分活度、营养因子、脱毒酶激活方法等发酵工艺进行进一步优化，实现脱毒效率的提升。<br>