The essence of crystallization is the process of precipitating solute by cooling with hot saturated solution, and then the solute appears in the form of crystal. Evaporation, cooling and salting out are the most common crystallization methods. The most common operation in crystallization is stirring, and the speed of stirring has a great influence on the appearance of crystals. In addition, the factors affecting the crystallization are the evaporation rate, the cooling rate and the rate of adding the solvent. The solvent selected for crystallization should have the characteristic of increasing the dissolving power with the increase of temperature and the ability to dissolve a part of impurities at low temperature.
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