Of note, all 21 patients included i

Of note, all 21 patients included in our systematic review had adenocarcinoma of the lung and all of them had also been treated with chemotherapy. Certainly, the appropriate indications for this type of surgery are mandatory to obtain longer survival. Surgical indications in this group of patients could be proposed as summarised in table 2. The exclusion of N2 and N3 patients is mandatory, and therefore correct histology of mediastinal nodes prior to surgery is obligatory. In the case of PET-positive N2 or N3, the standard protocol must include EBUS and/or video-mediastinoscopy to guarantee that no patient is denied surgery because of a false-positive PET scan or enlarged nodes on CT