The bottom mud of shrimp culture pond contains not only microcystin but also microorganisms that can degrade microcystin. The removal of MCS by microorganisms has the advantages of low cost, strong safety and ecological restoration. It is a promising method to remove MCS [14]. In this experiment, we studied the purification of microcystins in laboratory, and obtained enough microcystins. They were used to configure selective medium for the growth of carbon and nitrogen sources, and then screened out the bottom microorganism which can degrade microcystin. The degradation performance of the sediment microorganism under aerobic condition was studied by changing the external environment of the microorganism growth, and the degradation performance of MC LR with initial concentration of 1.035 was studied. The degradation rate of MC LR in 96h was measured, and the degradation performance of the bottom mud microorganism was directly understood under aerobic environment. In this experiment, it was found that the degradation rate of MC LR increased gradually with the increase of time, reaching 14.49% at 96h. The results showed that the microorganism in the sediment had a strong aerobic degradation ability to microcystin.<br>
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