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Older patients were more likely to
Older patients were more likely to discontinue neratinib treatment due to diarrhoea. The incidence of acute renal failure was also increased in this population. Older patients are at increased risk of complications of diarrhoea, including renal impairment, and should be carefully monitored. Rash and PPE syndrome were reported more commonly by Asian patients compared to White patients. Patients with mild renal impairment were more likely to discontinue treatment due to diarrhoea and dehydration, and should be carefully monitored if diarrhoea develops.
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老年患者更可能中止治疗那替尼因腹泻。急性肾功能衰竭的发病率在这个人口也有所增加。老年患者在腹泻的并发症，包括肾功能损害的风险增加，应仔细监测。皮疹和PPE综合征是由亚洲患者报告更普遍比白人患者。患者有轻度肾功能损害更可能中断治疗因腹泻和脱水，并应如有腹泻开发仔细监测。
正在翻译中..
Older patients were more likely to discontinue neratinib treatment due to diarrhoea. The incidence of acute renal failure was also increased in this population. Older patients are at increased risk of complications of diarrhoea, including renal impairment, and should be carefully monitored. Rash and PPE syndrome were reported more commonly by Asian patients compared to White patients. Patients with mild renal impairment were more likely to discontinue treatment due to diarrhoea and dehydration, and should be carefully monitored if diarrhoea develops.
正在翻译中..
老年患者更可能因腹泻而停止尼拉替尼治疗。急性肾功能衰竭的发生率在这一人群中也有所增加。老年患者出现腹泻并发症（包括肾损害）的风险增加，应仔细监测。与白人患者相比，亚洲患者更常报告皮疹和PPE综合征。轻度肾功能损害的患者更可能因腹泻和脱水而停止治疗，如果出现腹泻，应仔细监测。
正在翻译中..
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