Aldose reductase activates PKC-δ, and the PKC-δ/p38 αMAPK pathway induces pericyte apoptosis and cell-free capillary formation by inhibiting VEGF [66];
Aldose reductase activates PKC- δ, PKC- δ /p38 αMAPK pathway, which leads to apoptosis of pericytes and formation of acellular capillaries by inhibiting VEGF [66];