[摘要]目的：研究叉头转录因子蛋白——FoxM1在宫颈癌组织中的表达与

[Abstract] Objective: Relationship between forkhead transcription factor protein expression with clinical characteristics --FoxM1 in the cervical cancer. Methods: March 2017 - May 2019 Court biopsies, cervical cancer tissue samples obtained as 106 cases of cervical cancer surgery, alternatively the same period obtained as 50 healthy normal cervical tissue, immunohistochemical staining method for protein expression FoxM1 two specimens for testing, using SPSS26.0 statistical software. the results were calculated and analyzed to investigate the relationship table features and clinical characteristics of patients FoxM1 protein in cervical carcinoma. Results: In groups of cervical tissue were detected positive FoxM1 protein, and the positive rate of cervical cancer was significantly higher than the control group (P <0.05); FIGO stage Ⅱ, moderately differentiated, and the height of myometrial invasion ≥ 1/2 lower, the positive rate of FoxM1 proteins are significantly higher than that of FIGO stage ⅰ, poorly differentiated, positive rate of myometrial invasion <1/2, and (all P <0.05). Conclusion: FoxM1 protein is highly expressed in cervical cancer, and the expression of this protein is closely related to the clinical features of clinical stage, myometrial infiltration degree of a patient with.

Objective: To study the relationship between the expression and clinical characteristics of the fork-head transcription factor protein FoxM1 in cervical cancer tissue. Methods: Select edgy 106 cervical cancer tissue samples obtained from biopsies and operations in the hospital from March 2017 to May 2019 as the cervical cancer group, and 50 normal cervical tissues obtained during the same period as the normal group, test the expression of FoxM1 protein in two groups of specimens using immunohistized dying method, and use SPSS26.0 statistical software to analyze the results of the test results, and explore the characteristics of FoxM1 in the clinical conditions of cervical cancer. Results: Positive FoxM1 protein was detected in both groups of cervical tissue, and the positive rate in the cervical cancer group was significantly higher than that of the normal group (P 0.05), FIGO phase II, height and moderate differentiation, and the positive rate of FoxM1 protein was significantly higher than that of FIGO phase I, low differentiation, and 1/2 of the muscle-soaked (all 0P.0P). Conclusion: The FoxM1 protein is highly expressed in cervical cancer tissue, and the expression of the protein is closely related to the clinical characteristics of clinical staging and leaching of the muscle layer.

[Abstract] Objective: To study the relationship between the expression of forkhead transcription factor protein FoxM1 and clinical features in cervical cancer. Methods: from March 2017 to may 2019, 106 samples of cervical cancer obtained by biopsy and operation in our hospital were selected as cervical cancer group, and 50 samples of normal cervical tissue obtained at the same time were selected as normal group. The expression of FoxM1 protein in the two groups of samples was detected by immunohistochemical staining, and the results were calculated and analyzed by spss26.0 statistical software to explore the FoxM1 protein in the palace The relationship between the surface characteristics of cervical cancer and the clinical characteristics of patients. Results: positive FoxM1 protein was detected in cervical tissues of both groups, and the positive rate in cervical cancer group was significantly higher than that in normal group (P. Conclusion: FoxM1 protein is highly expressed in cervical cancer, and its expression is closely related to the clinical stage of patients and the degree of myometrial invasion.<br>