Fig. 8 (a) Sketch map for the working mechanisms of iMIPT and theNPs of iMIPT molecule for PA imaging. (b) Temperature changes forthe solutions of 18 NPs as a function of time upon irradiation with808 nm laser (0.8 W cm ?2 ) for 300 s. Inset: IR thermal images of 18NPs upon exposure to 808 nm (0.8 W cm ?2 ) laser irradiation fordifferent times. (c) PA intensity of tumors and muscle tissues asa function of time before (0 h) and after intravenous injection of 18NPs. Inset: PA images of tumors and muscles from 18 NPs-adminis-trated mice after 18 NPs (300 mM based on 18) were intravenouslyinjected into xenograft 4T1 tumor-bearing mice for 4 h. Data adaptedwith permission. 85 Copyright, 2019, Nature Publishing Group.