these datademonstrated a significant reduction in proteins synthesized from glucose (Fig. 3A); however, whileglobal translation was reduced, we also queried the global proteome to identify proteins thatincreased, rather than decreased under ischemia.Remarkably, higher peptide levels were detectedfor almost all enzymes directly involved in glycolysis in HCC cell populations grown under ischemia compared to HCC cells grown under standard conditions (Fig. 3B).