Table 1 Clinical features of CRSOrgans/systems SyndromesGeneral symptoms Fever, fatigueLung Tachypnea, hypoxia, pulmonary edema, respiratory failureBlood Cytopenias, coagulopathy, febrile neutropenia, disseminated intravascular coagulationHeart Tachycardia, hypotension, troponin elevation, arrhythmia, QT prolongation, stress, cardiomyopathy, acute heart failureLiver Hepatomegaly, elevated liver enzymes, hypofibrinogeniemia, liver failureKidney Acute kidney injury, renal failureCentral nervous system Headaches, confusion, hallucinations, delirium, aphasia, paresis, seizuresIleum DiarrheaMusculoskeletal system Myalgia, arthralgia, rigor, rash, edemaStomach Nausea, vomitingSpleen Splenomegaly