选取2018年1月至2021年7月于湖北省荆州市中心医院儿科病区就诊的

选取2018年1月至2021年7月于湖北省荆州市中心医院儿科病区就诊的128例脓毒症患儿，并根据疾病严重程度分为轻度脓毒血症组71例和重度脓毒血症57例作为试验组，另外随机选取同期入住我院儿科病区非脓毒症感染的患儿126例作为局部感染对照组；通过本院电子病历系统收集试验组及对照组的检测数据以及相关的临床资料进行统计学分析；采用Spearman相关分析血清PA、RBP检测水平与脓毒血症病情严重程度的相关性；绘制受试者工作特征曲线(ROC曲线)评价PA、RBP和PCT对儿童脓毒血症的早期诊断效能。

128 children with sepsis treated in the pediatric ward of Jingzhou Central Hospital of Hubei Province from January 2018 to July 2021 were selected and divided into 71 cases of mild sepsis group and 57 cases of severe sepsis group according to the severity of the disease as the experimental group. In addition, 126 children with non sepsis infection admitted to the pediatric ward of our hospital in the same period were randomly selected as the local infection control group; The test data and relevant clinical data of the experimental group and the control group were collected through the electronic medical record system of our hospital for statistical analysis; Spearman correlation analysis was used to analyze the correlation between the detection levels of serum PA and RBP and the severity of sepsis; The receiver operating characteristic curve (ROC curve) was drawn to evaluate the early diagnostic efficacy of PA, RBP and PCT in children with sepsis.

128 children with sepsis who visited the pediatric ward of Jingzhou Central Hospital in Hubei Province from January 2018 to July 2021 were selected and divided into mild sepsis group (71 cases) and severe sepsis group (57 cases) as the experimental group according to the severity of the disease. In addition, 126 children with non-sepsis infection who were admitted to the pediatric ward of our hospital at the same time were randomly selected as the local infection control group. Through the electronic medical record system of our hospital, the test data of the experimental group and the control group and related clinical data were collected and statistically analyzed. Spearman correlation was used to analyze the correlation between serum PA and RBP levels and the severity of sepsis. Draw receiver operating characteristic curve (ROC curve) to evaluate the efficacy of PA, RBP and PCT in early diagnosis of sepsis in children.