. Because of rapid uptake of bothfluorophores in AGs (within 5 min), injections can be repeatedintraoperatively, if needed, to keep the signal strong throughout thesurgical procedure. What is not known, though, is how they willperform in the setting of adrenal tumors. Tumors in the medulla areless likely to exhibit high uptake based on our histological data.Tumors of the adrenal cortex may exhibit high uptake, in which casethese NIR fluorophores could be used to find local and distantmetastases.