Leakage, for a sterile preparation,

Leakage, for a sterile preparation, means the entry of outside air, which will bring fungi, bacteria, etc. As a result, microbial contamination occurs, or endotoxin exceeds the standard. Once used, the endotoxin will cause fever in patients at mild cases, and systemic blood infection in severe cases. This point of view has been confirmed in the analysis of the causes of clinical infusion reactions. The hidden danger of large-volume injection leakage is the leakage of liquid medicine caused by poor sealing. Leakage of injections is not just a simple large amount of liquid leakage, but also minor leakage that is not easy to detect with the naked eye. Leakage will result in microbial contamination of the product, endangering patient safety.