Lung cancer is one of the most common types of malignant tumors, and its mortality rate is the leading cause of cancer death. D-d polymer is the degradation product of cross-linked fibrin by fibrous lysase, and its increase reflects the high coagulation state and fiber-soluble activity enhancement of blood in the body, which is one of the most sensitive and accurate indicators at present, and is the only index that directly reflects the production of clotting enzymes and fibrosolyzymes. In this study, by collecting exosome blood samples from patients with initial diagnosis of NSCLC, NSCLC patients were diagnosed by pathology and tested for changes in the level of exosome D-D-D polymer before and after surgery in NSCLC patients, follow-up for 2 years, The recurrence metastasis rate of tumor after surgery was recorded, and the relationship between it and clinical stage and tissue differentiation was discussed, and the relationship between preoperative and postoperative weekly blood D-polymer level and relapse metastasis in patients after NSCLC was analyzed by ROC curve.
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