In this graduation project, all the units in the production flow chart of offset printing books and periodicals paper were separately calculated for the slurry water balance, and a detailed sheet of slurry water balance was drawn according to the calculation results of slurry water balance.According to the calculation results of pulp water balance and the detailed list of pulp water balance, this design carries out equipment selection and calculation of the number of machines and specific equipment used in the production process, and draws a list of equipment.According to the layout principle of paper making workshop and the calculation of equipment selection, the specific length, height, span and other important dimensions of production workshop are determined.According to the data of slurry water balance calculation, equipment selection and calculation, workshop layout principles and design and requirements of workshop layout, four drawings of slurry water balance diagram, process flow diagram, plant layout diagram and workshop layout (plane and elevation) are drawn. The offset printing book paper made this time uses 30% bleached hardwood wood pulp board as the raw material. At the same time, 70% chemimechanical pulp is used in order to make the high smoothness, elongation, tensile energy absorption (TEA), tear resistance, breakage resistance, air permeability and printability indexes of the finished offset printing book paper reach international standards and maintain continuous production and control costs.There are some unsatisfactory aspects in this design process, but in real time when the factory is put into production, follow-up supplements will be made to reduce those deficiencies.