In this paper, the prediction model of the nearest adjacent yarn knot and the BP neural network prediction model are used to predict the cotton knot index of fine yarn varieties, and the prediction effect of the two prediction methods is analyzed according to the average relative error of the prediction data set and the average square root error.In this paper, the grey correlation nearest neighbor yarn nep prediction model and BP neural network prediction model are used to predict the NEP index of spinning varieties, and the prediction results of the two prediction methods are compared and analyzed according to the average relative error and root mean square error of the prediction data set.