Our microarray analysis revealed the circRNA expression profiles in five paired human HCC and paratumorous tissues (GEO No. 94508: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE94508). The box plot is a direct way to rapidly visualize the distributions of adataset for the circRNAs profiles. After normalization, the distributions of log2 ratios among ten samples are nearlythe same (Figure 1A). Differentially expressed circRNAswith statistical significance (fold changes ≥2.0 andP