Before the introduction of my study, I would like to show two images of colonoscope. This is normal colon mucosa from a healthy male. Flat, smooth mucosa without lesions. Then let’s move on to the next. This was from a 20-year old young man with the most severe UC. Apparently, erosions, ulcers, and spontaneous bleeding distributed along the lumen. It is estimated that over 3 million individuals are affected by IBD in Europe.