2) 设计并合成了葡萄糖酸修饰的柱[5]芳烃，通过核磁共振波谱、质谱对

2) 设计并合成了葡萄糖酸修饰的柱[5]芳烃，通过核磁共振波谱、质谱对其结构进行了表征。同时通过全葡萄糖酸修饰的柱[5]芳烃（GP5）与抗癌药硼替佐米（BTZ）形成的硼酸酯键制备了一种对酸碱度敏感的靶向多糖结合物，并对其刺激响应释放和体外细胞毒性进行了研究。

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结果 (英语) 1: [复制]

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2) Designed and synthesized gluconic acid-modified column [5] aromatic hydrocarbon, and characterized its structure by nuclear magnetic resonance spectroscopy and mass spectrometry. At the same time, a phosphate-sensitive targeted polysaccharide conjugate was prepared through the borate bond formed by the column [5] aromatic hydrocarbon (GP5) modified with whole gluconic acid and the anticancer drug bortezomib (BTZ), and responded to its stimulation. Release and in vitro cytotoxicity were studied.

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结果 (英语) 2:[复制]

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2) The gluconic acid modified column is designed and synthesized with aromatic hydrocarbons, and its structure is indicated by MRI spectrometry and mass spectrometry. At the same time, a targeted polysaccharide binding sensitive to acidity and alkalinity was prepared by the borate bond formed by the column of full glucosic acid modification (GP5) and the anti-cancer drug boronitazome (BTZ), and its stimulation response release and in vitro cytotoxicity were studied.

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结果 (英语) 3:[复制]

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2) Gluconic acid modified column [5] arene was designed and synthesized, and its structure was characterized by NMR and MS. At the same time, a pH sensitive targeted polysaccharide conjugate was prepared by the borate ester bond formed by the whole gluconic acid modified column [5] arene (GP5) and the anticancer drug bortezomib (BTZ), and its stimulation response release and cytotoxicity in vitro were studied.<br>

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