The results are consistent with the predicted function of HGT-KAPs. It has been reported that thecontent of HGT-KAPs is decreased in Merino felting luster (FL) mutant wool that loses crimp [17], andthat the helical angle of IFs in the orthocortex is associated with fiber curvature [18]. The HGT-KAPsare predominantly present in the orthocortex and are thought to have some associations with thecrimp of wool fiber [19]. The results from this research confirm that variation in KRTAP22-1 may affectthose traits.