However, many core tasks in health care, such as clinical risk prediction, diagnostics, and therapeutics, are more challenging for AI applications. For many clinical syndromes, such as heart failure or delirium, there is a lack of consensus about criterion standards on which to train AI algorithms. In addition, many AI techniques center on data classification rather than a probabilistic analytic approach; this focus may make AI output less suited to clinical questions that require probabilities to support clinical decision making.4 Moreover, AI-identified associations between patient characteristics and treatment outcomes are only correlations, not causative relationships. As such, results from these analyses are not appropriate for direct translation to clinical action, but rather serve as hypothesis generators for clinical trials and other techniques that directly assess cause-and-effect relationships.