There are many applications of hybrid GNPs in biological imaging. Due to the appropriate tolerance and compatibility of mixed GNPs in cell and tumor microenvironment, people are increasingly interested in the use of mixed GNPs. X-ray computed tomography is a non-invasive method, which uses mixed GNPs to enhance the absorption of other convenient organic molecules. Mixing GNPs as a contrast agent provides higher X-ray absorption, controllable size and shape, and the possibility of surface modification [18].<br>
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